Bradykinin in carcinoid syndrome.
نویسندگان
چکیده
منابع مشابه
Bradykinin in carcinoid syndrome.
Bradykinin concentrations in peripheral venous blood were measured in seven patients with carcinoid syndrome. The diagnosis was based on typical symptoms and raised urinary excretion of 5-hydroxy-3-indole acetic acid; the carcinoid tumour was verified histologically. Two patients were flushing constantly and the other patients had flushing attacks two to 10 times daily. Several blood samples we...
متن کاملEvidence for the release of bradykinin in carcinoid syndrome.
In a previous report (2), it was shown that a kinin peptide was released into the hepatic venous blood of some patients with carcinoid syndrome during flushes induced by epinephrine. A kinin-forming enzyme (kallikrein) was found in several carcinoid tumors. The kinin obtained from the hepatic venous blood of these patients has been further examined in the present studies. The physicochemical ch...
متن کامل[Leonine facies in carcinoid syndrome].
Carcinoid syndrome is a rare disorder caused when elevated levels of vasoactive substances secreted by a carcinoid tumor fail to be metabolized by the liver. This can occur for a variety of reasons including metastatic invasion of the organ. Carcinoid syndrome results in elevated levels of 5-hydroxyindoleacetic acid in the urine. Clinical manifestations include: flushing, diarrhea, bronchospasm...
متن کاملEndobronchial Carcinoid and Concurrent Carcinoid Syndrome in an Adolescent Female
Endobronchial carcinoid tumors are the most common intrabronchial tumors in children and adolescents. Common signs and symptoms include persistent cough and wheezing not responsive to bronchodilators, hemoptysis, and recurrent fever. Diagnosis is frequently made by imaging and direct visualization with flexible bronchoscopy; surgery remains the gold standard treatment, and lung-sparing resectio...
متن کاملThe Carcinoid Syndrome
THE first description of a carcinoid tumour was as early as 1888 (Lubarsch). Later attention was drawn to the possibility that the cells of these tumours (known as argentaffinomas) act as secretors of some "endocrine" substance. "Enteramine" or "serotonin" (5 hydroxytryptamine or 5 H.T.) was later isolated from carcinoid tumours and recently its degradation product-5 hydroxy-indoleacetic acid o...
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ژورنال
عنوان ژورنال: Gut
سال: 1987
ISSN: 0017-5749
DOI: 10.1136/gut.28.11.1417